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Related projects

15/10/2019 Animal health

INNOTUB: Trans-Pyrenean research and development network of innovative tools for the control of animal tuberculosis.

01/10/2019 Animal health

MONBOVI: Pilot test for the monitoring of dairy cows health indicators in Catalonia

01/10/2019 Animal health

RECAMPY: Impact of the reduction of the use of antibiotics in poultry keeping in the presence of resistant Campylobacter spp

HEXOVAC: Exosome-deived quasi-enveloped virus particles as candidate for novel hepatitis A and E vaccines.

Starting date: 21/06/2019 End date: 20/06/2022
Programme: Animal Health

Principal investigator:

Fernando Rodríguez Fernando Rodríguez 93 467 40 40 (center) Ext.

Financing entities:

The present proposal addresses four main objectives:
  1. Development of methodologies to improve the production and purification of a fast-growing HAV strain in cell cultures used in vaccine manufacturing. Antigenic characterization of naked and pseudo-enveloped-particles.
  2. Characterization of the immunogenic properties in mice of HAV pseudo-enveloped-particles compared with nakedparticles.
  3. Evaluation of the protective effect generated by a potential vaccine based on pseudo-enveloped particles, compared to naked-particles, in a mouse model of hepatitis A infection.
  4. Characterization of the immunogenic properties in pigs of HAV pseudo-enveloped-particles compared with nakedparticles.

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